Efficiently detects Mr 83,000 Plakoglobin, a 'band 5' intercellular junction polypeptide (also known as gamma-catenin). Ideal for various intercellular junctions like desmosomes in epithelial and myocardial cells, zonulae and fasciae adherentes in epithelia, endothelia, and myocardial cells, and adherens-type junctions in tissues like lens, retina, and testis. Particularly beneficial for investigating plakoglobin mutations in cardiomyopathies, such as ARVC.