Special Features
Alternative Names: Interleukin-1 alpha, IL-1α, BAF, IL-1F1, LAF, LEM, preinterleukin 1 alpha, pro-interleukin-1-alpha
Gene ID:
Source: E. coli-derived rat IL-1alpha protein, Ser115-Ser270
Molecular Mass: Approximately 17.8 kDa
Amino Acid Sequence: SAPHSFQNNL RYKLIRIVKQ EFIMNDSLNQ NIYVDMDRIH LKAASLNDLQ LEVKFDMYAY SSGGDDSKYP VTLKVSNTQL FVSAQGEDKP VLLKEIPETP KLITGSETDL IFFWEKINSK NYFTSAAFPE LLIATKEQSQ VHLARGLPSM IDFQIS
Tag: None
Appearance: Sterile, filtered, white, lyophilized (freeze-dried) powder
Purity: > 97% by SDS-PAGE and HPLC analyses
Biological Potency: ED50 < 0.005 ng/mL, specific activity > 2.0 × 108 IU/mg
Endotoxin Level: < 1.0 EU per 1 μg of protein by LAL method
Formulation: Lyophilized from a 0.2 μm filtered solution in 20 mM Tris, 150 mM NaCl, pH 8.5
Reconstitution: Centrifuge vial briefly, reconstitute in sterile water or BSA buffer, store at ≤ -20°C
Storage & Shipping: Shipped with ice pack, store at -20°C to -80°C for 1 year
Handling Caution: Avoid repeated freeze-thaw cycles
Safety: Wear lab coats and gloves for operation
Description
IL-1 alpha, also known as IL-1A or IL1, is a cytokine belonging to the interleukin-1 family. Its mature amino acid sequence is conserved between 60% to 70% across species, with human IL-1 showing biological activity on murine cell lines. It exhibits metabolic and physiological properties, including hematopoiesis.
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