Disrupts Microtubule Networks: Effective at 9 µM in V79 Cells
Inhibits Cell Proliferation: 92% Reduction at 20 µM
Regulates Cholesterol & Weight Loss in High-Cholesterol Diet Rats
Quantification Standard: 17β-Estradiol in Hen Urine
Description
3-O-methyl Estradiol, a synthetic estrogen, disrupts microtubule networks in V79 Chinese hamster cells (EC 50 = 9 µM) and inhibits their proliferation by 92% at 20 µM. In male rats on a high-cholesterol diet, it reduces serum cholesterol levels and promotes body weight loss, demonstrating feminizing activity. It has served as a standard for quantifying 17β-estradiol in hen urine.
