SBE 13 هيدروكلوريد 50 ملغ من شركة كايمان كيميكال
مميزات خاصة
Highly effective Plk1 inhibitor (IC50 = 0.2 nM), targets enzyme's inactive form
No impact on aurora A kinase
Less potent against Plk2 (IC50 > 66 µM)
Less potent against Plk3 (IC50 = 875 nM)
Triggers cell cycle arrest
Slows down cell proliferation
Induces cell death
وصف
A powerful inhibitor of Plk1 (IC50 = 0.2 nM), targeting its inactive form; shows no activity against aurora A kinase, and less effectively inhibits Plk2 (IC50 > 66 µM) and Plk3 (IC50 = 875 nM); triggers cell cycle arrest, reduces cell proliferation, and induces apoptosis.
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