Insect cells facilitate high protein expression with post-translational modifications akin to mammalian cells, easy scalability, and simplified cell growth, adaptable to high-density suspension culture for large-scale production. Many mammalian post-translational modification pathways are present in insect cells, enabling recombinant protein production that's more similar to native mammalian proteins than expression in yeast or other eukaryotes. Baculovirus expression systems are potent and versatile tools for high-level recombinant protein expression in insect cells, with reported expression levels up to 500 mg/L.