During perimenopause and menopause, women experience symptoms when extreme shifts occur in the sex hormones estrogen, progesterone and testosterone. As hormonal ratios and balance are disrupted beyond their normal ranges, you may first sense that something is "off" or "not quite right" in your body. As hormonal imbalance intensifies, you will begin to suffer from symptoms ranging from mild to severe, such as: Drenching night sweats Dizzying hot flashes Low energy Weight gain Irritability Irregular periods Low libido Sleepless nights