Nasal Decongestant. Won't Drip From Nose or Down Throat. Compare to Afrin original active ingredient. Nasal Spray Oxymetazoline HCL 0.05%, maximum strength, provides fast, powerful congestion relief for allergies and colds for up to 12 hours. Nasal Decongestant Won't Drip From Nose or Down Throat. Offers immediate and effective sinus and allergy relief. Nose spray is a quick and easy OTC method for sinus pressure relief and nasal decongestion. it's cat allergies that have you stuffy, or the common cold, experience powerful and rapid 12 hour relief with Reliable-1's nose spray