Tailored miRNA target site blockers for specific inhibition
Advanced design with superior affinity, regardless of target sequence
Unparalleled in vitro and in vivo effectiveness
Exceptional performance and high protein expression, no RNase H-dependent mRNA degradation
Highly efficient at low concentrations, outcompetes miRNAs for target sites
Superior biological stability for sustained antisense activity
وصف
miRCURY LNA miRNA Power Target Site Blockers are antisense oligonucleotides that attach to the miRNA target site of an mRNA, blocking miRNAs from accessing it. This enables researchers to examine the effects of an miRNA on a single target. Conversely, inhibiting an miRNA reveals its collective impact on all targets. These blockers can help identify which pathway is involved in a phenotype resulting from miRNA inhibition, or which miRNA/mRNA interactions are most significant in a pathway with multiple predicted targets.
