This medication is used to treat vaginal yeast infections. Miconazole reduces vaginal burning, itching, irritation and discharge that may occur with this condition. It works by stopping the growth of yeast (fungus) that causes the infection. Ask your doctor before using this medication for self-treatment if this is your first vaginal infection. This medication only works for vaginal fungal infections. You may have a different type of infection (such as bacterial vaginosis) and may need a different medication. If you have fever, chills, flu-like symptoms, stomach/abdominal pain, or a bad-smelling vaginal discharge, do not use this medication. Contact your doctor right away because these may be signs of a more serious infection.