Biotest's Micellar Curcumin solid lipid curcumin particles produce 95 times more free curcumin in the bloodstream than highly pure, standardized curcumin (Gota VS et al, 2010). That's a bold claim. Fortunately, the formula's solid lipid curcumin particles are backed up with convincing science, invented by neuroscientists at UCLA, funded by the University of California (Oakland) and the Federal Government, supported by peer-reviewed research on humans, and patented (9192644). In contrast, ordinary curcumin isn't soluble in the acidic pH of the stomach. When it reaches the neutral or alkaline environment of the large intestine, much of it is made water-soluble and converted into inactive waste by glucuronidation, which is how the body rids itself of most pollutants and . Some raw curcumin makes it through the large intestine intact, but then it's subjected to further metabolism by the colon's bacteria. A small amount eventually gets absorbed into the bloodstream, but much of it gets metabolized by liver cells and eliminated through bile. All of this means you can take as many as six or more capsules of ordinary curcumin, and you wouldn't be able to find even a trace of its free form circulating in the bloodstream an hour later