Benadryl Extra Strength Itch Cooling Spray provides relief from skin pain and itching. Made with 2% diphenhydramine HCI topical analgesic and 0.1% zinc acetate skin protectant, this spray begins to work on contact to relieve the pain and itching associated with insect bites, sunburn, scrapes, and minor skin irritations, burns, and cuts. It also treats and dries rashes caused by poison ivy, poison oak, and poison sumac by blocking the histamine that causes the itch. Benadryl Extra Strength Itch Cooling Spray and is intended for ages two and up.