Garcinia cambogia is a plant native to southeast Asia that has been used for centuries by traditional herbalists. Garcinia's primary bioactive constituent, hydroxycitric acid (HCA), has been extensively studied for its effects on citrate lyase, which is the main enzyme responsible for the cellular synthesis of fatty acids. Scientific studies indicate that in the presence of HCA, cells produce fewer fatty acids from carbohydrates.* NOW® Garcinia is standardized to 50% HCA and tested to guarantee 500 mg HCA per tablet. Natural color variation may occur in this product.