The Dymo-Spin III-S can be used in centrifuges or on vacuum manifolds for the purification of plasmid DNA. Exclusive to this column is a Lure-Lock bottom assembly and conical tip. The Dymo-Spin III-S features durable polypropylene construction and a unique silica-based matrix that allows for purification of up to 10 mg of plasmid DNA in = 2 ml eluate when used in combination with Plasmid Prep buffers. Capacity is 15 ml and can be increased to 615 ml when used in conjunction with the 600 ml reservoir.