The maritime pine tree is endogenous to the western Mediterranean region. Pycnogenol is the trade name for the extract of the bark of the French maritime pine tree. This pine bark extract is one of the most potent antioxidant compounds ever discovered and considered by many experts to be the nutritional breakthrough of the 20th century.** Pycnogenol works synergistically with Vitamins C and E to help your body assault free radicals.** Pycnogenol also bolsters the immune system, helps improve circulation in legs (specifically in the veins and capillaries), supports the heart, nourishes the skin, and may help remedy the occasional discomforts of PMS.** Pycnogenol is a registered trademark of Horphag Research Ltd. ** These statements have not been evaluated by the Food and Drug Administration. These products are not intended to diagnose, treat, cure or prevent any disease.