Compare to Vicks DayQuil Severe and Vicks NyQuil Severe active ingredients. Daytime and Nighttime Maximum Strength Severe Cold and Flu Relief is a combo pack that offers maximum strength relief for your cold and flu symptoms, day and night. Daytime Severe in original flavor provides non-drowsy relief of aches, fever, cough, nasal congestion, sore throat and chest congestion. Daytime is alcohol and antihistamine free. Nighttime Severe is a sugar free, mixed berry flavored liquid that relieves aches, pain, fever, sore throat, cough, sneezing, runny nose, nasal/sinus congestion and sinus pressure so you can rest. This combo pack provides around-the-clock multi-symptom relief.