كايمان الكيميائية 98N12-5
وصف
98N12-5, an ionizable cationic lipid, has been employed with other lipids to create lipid nanoparticles (LNPs). These LNPs, encapsulating PCSK9 siRNA, selectively target the liver, reducing total serum cholesterol in mice and rats, and LDL levels in cynomolgus monkeys.
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