Each can is equivalent to 8 ounces of R1234YF! This refrigerant can be charged under a vacuum. This product was designed and developed to meet the needs for colder air for some applications in auto, agriculture and commercial applications. Ed's Distribution R1234YF Replacement Refrigerant will work in small vehicles, sedans, minivans, SUVs, and large SUVs (Suburbans & Expeditions, etc), systems with dual air and even includes semi tractors. This refrigerant also works for agriculture needs (tractors, combines, etc) and other pieces of equipment where greater cooling is required because of hydraulic lines under the drivers seat or on top of the cab. Anything with a lot of glass makes this a perfect refrigerant! This refrigerant can also be used in applications such as milk houses, cooling tanks, pasturizing equipment, water coolers, soda machines, ice machines, refrigerators, and dehumidifers are just a small list. Basically, anything that already has R1234YF in it or anything that has been retrofitted to R1234YF. Ed's Distribution R1234YF Replacement Refrigerant can replace R1234YF. NOT FOR USE IN AMMONIA SYSTEMS! This is our coldest refrigerant we have for automotive use in hot climates with high humidity. About 5° colder than Ed's Distribution R1234YF Replacement Refrigerant with Dye. Operates at lower head pressure Offers improved cooling properties and performance Compatible with most refrigerant oils Non Ozone depleting Non Global warming R1234YF can thread Use up to 60% Less Made in America! R1234YF has been manufacturing hydrocarbon refrigerants since 1996. Flammable to an open flame or spark and proceed with caution if used in systems designed for non-flammable refrigerants