Nix out Super Lice. Nix Ultra All-in-1 Super Lice Shampoo kills head lice and eggs (nits), including hard-to-kill Super Lice. From the Number One pediatrician-recommended lice removal brand (1), this shampoo effectively eliminates head lice. Nix Ultra All-in-1 Super Lice Shampoo is specifically designed to kill Super Lice, which have developed resistance to many traditional lice treatments. First, apply Nix Ultra All-in-1 Super Lice Shampoo to hair. Then, remove lice and eggs (nits) from head hair with the Nix Professional Lice Removal Comb. Nix Ultra All-in-1 Super Lice Shampoo is for use on head hair and safe for use on children 1 year and older. It's also a cleanser, so no additional shampoo step is needed. Nix is trusted by moms and feared by lice. See the package insert for full instructions and read entire label before each use. (1) Pediatrician survey data on file.